论文

•  Angelovski, G. ,Tickner, B.J. & Wang, G. (2023) Opportunities and challenges with hyperpolarized bioresponsive probes for functional imaging using magnetic resonance. Nat. Chem. 15: 755–763
•  Wang, G., Martin, H., Amézqueta, S.; Ràfols, C.; Bonnet, C.* and Angelovski, G.* (2022) Insights into the Responding Modes of Highly Potent Gadolinium-Based Magnetic Resonance Imaging Probes Sensitive to Zinc Ions. Inorg. Chem. 61: 16256-16265
•  Tickner, B., Platas-Iglesias, C., Duckett, S., Angelovski, G. (2022) In Situ Ternary Adduct Formation of Yttrium Polyaminocarboxylates Leads to Small Molecule Capture and Activation. Chem. Eur. J. : e202201780
•  Pérez-Lourido, P., Madarasi, E., Antal, F., Esteban-Gómez, D., Wang, G., Angelovski, G., Platas-Iglesias, C.*, Tircsó G., and Valencia, L.* (2022) Stable and inert macrocyclic cobalt(II) and nickel(II) complexes with paraCEST response. Dalton Trans. 51: 1580-1593
•  Fehling, P., Buckenmaier, K., Dobrynin, S., Morozov, D., Polienko, Y., Khoroshunova, Y., Borozdina, Y., Mayer, P., Engelmann, H., Scheffler, K., Angelovski, G., Kirilyuk, I. (2021) The effects of nitroxide structure upon 1H Overhauser dynamic nuclear polarization efficacy at ultralow-field. J. Chem. Phys. 155: 144203
•  Gambino, G., Gambino, T., Connah, L., La Cava, F., Evrard, H., Angelovski, G.* (2021) RGD-Peptide Functionalization Affects the In Vivo Diffusion of a Responsive Trimeric MRI Contrast Agent through Interactions with Integrins. J. Med. Chem. 64: 7565-7574
•  Castro, G., Wang, G., Gambino. T., Esteban-Gómez, D., Valencia, L., Angelovski, G., Platas-Iglesias, C.* and Pérez-Lourido, P.* (2021) Lanthanide(III) complexes based on an 18-membered macrocycle containing acetamide pendants. Structural characterization and paraCEST properties. Inorg. Chem. 60: 1902-1914
•  Tickner, B., Borozdina, Y., Duckett, S.* and Angelovski, G.* (2021) Exploring the hyperpolarisation of EGTA-based ligands using SABRE. Dalton Trans. 50: 2448-2461
•  Wang, G. and Angelovski, G.* (2021) Highly potent MRI contrast agent displaying outstanding sensitivity to zinc ions. Angew. Chem. Int. Ed. 60: 5734–5738
•  Connah, L. and Angelovski, G.* (2020) Solid phase synthesis in the development of magnetic resonance imaging probes. Org. Chem. Front. 7: 4121-4141
•  Wang, G. and Angelovski, G.* (2020) Macrocyclic chelates bridged by a diaza‐crown ether: towards multinuclear bimodal molecular imaging probes. Molecules 25: 5019
•  Rodríguez-Rodríguez, A., Zaiss, M., Esteban-Gòmez, D., Angelovski, G.*, Platas-Iglesias, C.* (2021) Paramagnetic chemical exchange saturation transfer agents and their perspectives for application in magnetic resonance imaging. Int. Rev. Phys. Chem. 40: 51-79
•  Tickner, B., Stasiuk, G., Duckett, S., Angelovski, G.* (2020) The use of yttrium in medical imaging and therapy: historical background and future perspectives. Chem. Soc. Rev. 49: 6169-6185
•  Gambino, G., Gambino, T., Angelovski, G.* (2020) Combination of bioresponsive chelates and perfluorinated lipid nanoparticles enables in vivo MRI probe quantification. Chem. Commun. 56: 9433-9436
•  Gambino, T., Valencia, L., Pérez-Lourido, P., Esteban-Gòmez, D., Zaiss, M., Platas-Iglesias, C.*, Angelovski, G.* (2020) Inert macrocyclic Eu3+ complex with affirmative paraCEST features. Inorg. Chem. Front. 7: 2274-2286
•  Gambino, G., Gambino, T., Pohmann, R., Angelovski, G.* (2020) A ratiometric 19F MR-based method for the quantification of Ca2+ using responsive paramagnetic probes. Chem. Commun. 56: 3492-3495
•  Wang, G., Platas-Iglesias, C., Angelovski, G.* (2020) Europium(III) macrocyclic chelates appended with tyrosine‐based chromophores and di‐(2‐picolyl)amine‐based receptors: turn‐on luminescent chemosensors selective to zinc(II) ions. ChemPlusChem 85: 806-814
•  Garello, F., Gündüz, S., Vibhute, S., Angelovski, G.*, Terreno, E.* (2020) Dendrimeric calcium-sensitive MRI probes: the first low-field relaxometric study. J. Mater. Chem. B 8: 969-979
•  Toljić, Ð., Angelovski, G.* (2019) Translating a Low‐Molecular‐Weight MRI Probe Sensitive to Amino Acid Neurotransmitters into a PAMAM Dendrimer Conjugate: The Impact of Conjugation. ChemNanoMat. 5: 1456-1460
•  Savić, T., Gambino, G., Bokharaie, V., Noori, H., Logothetis, N.*, Angelovski, G.* (2019) Early detection and monitoring of cerebral ischemia using calcium-responsive MRI probes. PNAS 116: 20666-20671
•  Toljić, Ð., Angelovski, G.* (2019) A low-molecular-weight ditopic MRI probe for ratiometric sensing of zwitterionic amino acid neurotransmitters. Chem. Commun. 55: 11924-11927
•  Connah, L., Truffault, V., Platas-Iglesias, C., Angelovski, G.* (2019) Investigations into the effects of linker length elongation on the behaviour of calcium-responsive MRI probes. Dalton Trans. 48: 13546-13554
•  Toljić, Ð., Platas-Iglesias, C., Angelovski, G.* (2019) In-depth study of a novel class of ditopic gadolinium(III)-based MRI probes sensitive to zwitterionic neurotransmitters. Front. Chem. 7: 490
•  Connah, L., Joshi, R., Vibhute, S., Gambino, G., Correia, J., Angelovski, G.* (2019) Solid-phase-supported approach for the preparation of bioresponsive and multifunctional MRI probes. Org. Lett. 21: 5378-5382
•  Oukhatar, F., Eliseeva, S., Bonnet, C., Placidi, M., Logothetis, N., Petoud, S.*, Angelovski, G.*, Tòth, é.* (2019) Toward MRI and optical detection of zwitterionic neurotransmitters: near-infrared luminescent and magnetic properties of macrocyclic lanthanide(III) complexes appended with a crown ether and a benzophenone chromophore. Inorg. Chem. 58: 13619-13630
•  Pujales-Paradela, R., Savić, T., Esteban-Gomez, D., Angelovski, G.*, Carniato, F., Botta, M.*, Platas-Iglesias, C.* (2019) Gadolinium(III)‐based dual 1H/19F magnetic resonance imaging probes. Chem. Eur. J. 25: 4782-4792
•  Connah, L., Angelovski, G.* (2018) Synergy of key properties promotes dendrimer conjugates as prospective ratiometric bioresponsive magnetic resonance imaging probes. Biomacromolecules 19: 4668-4676
•  Gunduz, S., Vibhute, S., Botar, R., Kalman, F.*, Toth, I., Tircsò, G., Regueiro-Figueroa, M., Esteban-Gomez, D., Platas-Iglesias, C., Angelovski, G.* (2018) Coordination properties of GdDO3A-based model compounds of bioresponsive MRI contrast agents. Inorg. Chem. 57: 5973-5986
•  Zaiss, M.*#, Angelovski, G.#, Demetriou, E., McMahon, M., Golay, X., Scheffler, K. (2018) QUESP and QUEST revisited: fast and accurate quantitative CEST experiments. Magn. Res. Med. 79: 1708-1721
•  Angelovski, G.* (2017) Heading toward macromolecular and nanosized bioresponsive MRI probes for successful functional imaging. Acc. Chem. Res. 50: 2215-2224
•  Cakić, N., Tickner, B., Zaiss, M., Esteban-Gòmez, D., Platas-Iglesias, C.*, Angelovski, G.* (2017) Spectrally undiscerned isomers might lead to erroneous determination of water exchange rates of paraCEST Eu(III) agents. Inorg. Chem. 56: 7737-7745
•  Angelovski, G.*, Tòth, é. (2017) Strategies for sensing neurotransmitters with responsive MRI contrast agents. Chem. Soc. Rev. 46: 324-336
•  Gündüz, S.;Savi?, T.;?Tolji?, ?Angelovski, G.* (2016) Preparation and in vitro characterization of dendrimer-based contrast agents for magnetic resonance imaging. J. Vis. Exp. 118: e54776
•  Cakić, N., Savić, T., Stricker-Shaver, J., Truffault, V., Platas-Iglesias, C., Mirkes, C., Pohmann, R., Scheffler, K.*, Angelovski, G.* (2016) Paramagnetic lanthanide chelates for multicontrast MRI. Chem. Commun. 52: 9224-9227
•  Angelovski, G.* (2016) What we can really do with bioresponsive MRI contrast agents. Angew. Chem. Int. Ed. 55: 7038-7046
•  Gündüz, S., Savić, T., Pohmann, R., Logothetis, N., Scheffler, K., Angelovski, G.* (2016) Ratiometric method for rapid monitoring of biological processes using bioresponsive MRI contrast agents. ACS Sens. 1: 483-487
•  Garello, F., Vibhute, S., Gündüz, S., Logothetis, N., Terreno, E.*, Angelovski, G.* (2016) Innovative design of Ca-sensitive paramagnetic liposomes results in an unprecedented increase in longitudinal relaxivity. Biomacromolecules 17: 1303-1311
•  Cakić, N., Verbic, T., Jelić, T., Platas-Iglesias, C., Angelovski, G.* (2016) Synthesis and characterisation of bismacrocyclic DO3A-amide derivatives: an approach towards metal-responsive PARACEST agents. Dalton Trans. 45: 6555-6565
•  Regueiro-Figueroa, M., Gündüz, S.; Patinec, V., Logothetis, N., Esteban-Gòmez, D., Tripier, R., Angelovski, G.*, Platas-Iglesias, C.* (2015) Gd3+-based magnetic resonance imaging contrast agent responsive to Zn2+. Inorg. Chem. 54: 10342-10350
•  Moussaron, A., Vibhute, S., Bianchi, A., Gündüz, S., Kolb, S., Sancey, L., Motto-Ros, V., Rizzitelli, S., Crémillieux, Y., Lux, F., Logothetis, N., Tillement, O., Anglelovski, G.* (2015) Ultrasmall nanoplatforms as calcium-responsive contrast agents for magnetic resonance imaging. Small 11: 4900-4909
•  Oukhatar, F., Meudal, H., Landon, C., Logothetis, N., Platas-Iglesias, C., Angelovski, G.*, Toth, E.* (2015) Macrocyclic Gd3+ complexes with pendant crown ethers designed for binding zwitterionic neurotransmitters. Chem. Eur. J. 21: 11226-11237
•  Cakić, N., Gündüz, S., Rengarasu, R., Angelovski, G.* (2015) Synthetic strategies for preparation of cyclen-based MRI contrast agents. Tetrahedron Lett. 56: 759-765
•  Oukhatar, F., Même, S., Même, W., Szeremeta, F., Logothetis, N., Angelovski, G.*, Toth, E.* (2015) MRI sensing of neurotransmitters with a crown-ether appended Gd3+ complex. ACS Chem. Neurosci. 6: 219-225
•  Gündüz, S., Power, A., Maier, M., Logothetis, N., Angelovski, G.* (2015) Synthesis and characterization of a biotinylated multivalent targeted contrast agent. ChemPlusChem 80: 612-622
•  Gündüz, S., Nitta, N., Vibhute, S., Shibata, S., Maier, M., Logothetis, N., Aoki, I., Angelovski, G.* (2015) Dendrimeric calcium-responsive MRI contrast agents with slow in vivo diffusion. Chem. Commun. 51: 2782-2785
•  Kadjane, P., Platas-Iglesias, C., Boehm-Sturm, P., Truffault, V., Hagberg, G., Hoehn, M., Logothetis, N., Angelovski, G.* (2014) Dual-frequency calcium-responsive MRI agents. Chem. Eur. J. 20: 7351-7362
•  Angelovski, G.*, Gottschalk, S., Milošević, M., Engelmann, J., Hagberg, G., Kadjane, P., Andjus, P., Logothetis, N. (2014) Investigation of a calcium-responsive contrast agent in cellular model systems: feasibility for use as a smart molecular probe in functional MRI. ACS Chem. Neurosci. 5: 360-369
•  Placidi, M., Botta, M., Kálmán, F., Hagberg, G., Baranyai, Z., Krenzer, A., Rogerson, A., Tòth, I., Logothetis, N. K., Angelovski, G.* (2013) Aryl-phosphonate lanthanide complexes and their fluorinated derivatives: investigation of their unusual relaxometric behavior and potential application as dual frequency 1H/19F MRI probes. Chem. Eur. J. 19: 11644-11660
•  Vibhute, S., Engelmann, J., Verbić, T., Maier, M., Logothetis, N. K., Angelovski, G.* (2013) Synthesis and characterization of pH-sensitive, biotinylated MRI contrast agents and their conjugates with avidin. Org. Biomol. Chem. 11: 1294-1305
•  Placidi, M., Engelmann, J., Natrajan, L., Logothetis, N., Angelovski, G.* (2011) An aryl-phosphonate appended macrocyclic platform for lanthanide based bimodal imaging agents. Chem. Commun. 47: 11534-11536
•  Mamdedov, I., Logothetis, N., Angelovski, G.* (2011) Structure-related variable responses of calcium sensitive MRI probes. Org. Biomol. Chem. 9: 5816-5824
•  Henig, J., Mamedov, I., Fousková, P., Toth, E., Logothetis, N., Angelovski, G.*, Meyer, H.* (2011) Influence of calcium-induced aggregation on the sensitivity of aminobis(methylenephosphonate)-containing potential MRI contrast agents. Inorg. Chem. 50: 6472-6481
•  Angelovski, G.*, Mamedov, I. (2011) Cation-responsive MRI contrast agents based on gadolinium(III). Curr. Inorg. Chem. 1: 76-90
•  Kadjane, P., Logothetis, N., Angelovski, G.* (2011) A straightforward and convenient pathway for the synthesis of functional bismacrocyclic ligands. Tetrahedron Lett. 52: 1619-1622
•  Angelovski, G.*, Chauvin, T., Pohmann, R., Logothetis, N., Toth, E.* (2011) Calcium-responsive paramagnetic CEST agents. Bioorgan. Med. Chem. 19: 1097-1105
•  Mamedov, I., Canals, S., Henig, J., Beyerlein, M., Murayama, Y., Mayer, H., Logothetis, N., Angelovski, G.* (2010) In vivo characterization of a smart MRI agent that displays an inverse response to calcium concentration. ACS Chem. Neurosci. 1: 819-828
•  Mamedov, I., Parac-Vogt, T., Logothetis, N., Angelovski, G.* (2010) Synthesis and characterization of dinuclear heterometallic lanthanide complexes exhibiting MRI and luminescence response. Dalton Trans. 39: 5721-5727
•  Mamedov, I.*, Táborsky , P., Lubal, P.*, Laurent, S., Elst, L., Mayer, H., Logothetis, N., Angelovski, G.* (2009) Relaxometric, thermodynamic and kinetic studies of lanthanide(III) complexes of DO3A-based propylphosphonates. Eur. J. Inorg. Chem. 2009: 3298-3306
•  Angelovski, G.*, Fousková, P., Mamedov, I., Canals, S., Tòth, é.*, Logothetis, N. (2008) Smart magnetic resonance imaging agents that sense extracellular calcium fluctuations. ChemBioChem 9: 1729-1734
•  Mamedov, I., Mishra, A., Angelovski, G.*, Mayer , H.-A.*, Pålsson, L.-O., Logothetis, N. (2007) Synthesis and characterization of lanthanide complexes of DO3A-alkylphosphonates. Dalton Trans. : 5260-5267
•  Angelovski, G.*, Keränen, M., Linnepe, P., Grudzielanek, S., Eilbracht, P.* (2006) A rapid and reliable assay for regioselectivity using fluorescence spectroscopy. Adv. Synth. Cat. 348: 1193-1199
•  Angelovski, G., Keränen, M.*, Eilbracht, P.* (2005) Fluorescence screening of tartaric acid-derived azamacrocycles synthesized via sequential hydroformylation/reductive amination as potential ligands for asymmetric catalysis. Tetrahedron: Asymmetry 16: 1919-1926
•  Angelovski, G., Costisella, B., Kolarić, B.*, Engelhard, M., Eilbracht, P.* (2004) Complexation of metals with piperazine-containing azamacrocyclic fluorophores. J. Org. Chem. 69: 5290-5294
•  Angelovski, G., Eilbracht, P.* (2003) Synthesis of hydroquinone-, biphenol-, and binaphthol-containing aza macroheterocycles via regioselective hydroformylation and reductive amination. Tetrahedron 59: 8265-8274