论文
| • Zhang, J., Zhang, M., Wang, Q., Wen, H., Liu, Z., Wang, F., Wang, Y., Yao, F., Song, N., Kou, Z., Li, Y., Guo, F., Zhu, S.* (2023) Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits. Nature Structural & Molecular Biology. : In Press |
| • Lv, S., Yao, K., Zhang, Y., Zhu, S.* (2023) NMDA receptors as therapeutic targets for depression treatment: Evidence from clinical to basic research. Neuropharmacology. 225: 109378 |
| • Sun, H., Xu, X., Luo, J., Ma, T., Cui, J., Liu, M., Xiong, B., Zhu, S.*, Liu, J.* (2022) Mechanisms of PiT2-loop7 Missense Mutations Induced Pi Dyshomeostasis. Neurosci. Bull. In Press.: |
| • Zhang, Y#., Ye, F#., Zhang, T#., Lv, S., Zhou, L., Du, D., Lin, H., Guo, F., Luo, C.* & Zhu, S.* (2021) Structural basis of ketamine action on human NMDA receptors. Nature 596: 301-305 |
| • Wang, H., Lv, S., Stroebel, D., Zhang, J., Pan, Y., Huang, X., Zhang, X., Paoletti, P., Zhu, S.* (2021) Gating mechanism and a modulatory niche of human GluN1-GluN2A NMDA receptors. Neuron 109(15): 2443-2456.e5 |
| • Qu, R., Dong, L., Zhang, J., Yu, X.*, Wang, L.* & Zhu, S.* (2020) Cryo-EM structure of human heptameric Pannexin 1 channel Cell Res. 30(5): 446-448 |
| • Zhou Y, Liu Z, Zhang J, Dou T, Chen J, Ge G, Zhu S#, Wang F#. (2019) Prediction of ligand modulation patterns on membrane receptors via lysine reactivity profiling. Chem Commun 55: 4311-4314 |
| • Zhang, J.*, Chang, S., Xu, P., Miao, M., Wu, H., Zhang, Y., Zhang T, Wang, H., Zhang, J., Xie, C., Song, N., Luo, C.#, Zhang, X.#, Zhu, S.# (2018) Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors. Cell Rep. 25: 3582-3590 |
| • Zhu, S., Gouaux, E. (2017) Structure and symmetry inform gating principles of ionotropic glutamate receptors.(Invited review, Cover). Neuropharmacol. 112: 11-15 |
| • Zhu, S.*, Stein, RA., Yoshioka, C., Lee, CH., Goehring, A., Mchaourab, HS., Gouaux, E.# (2016) Mechanism of NMDA receptor inhibition and activation. Cell. 165(3): 704-714 |
| • Zhu S, Paoletti P. (2015) Allosteric modulators of NMDA receptors: multiple sites and mechanisms. Curr. Opin. Pharmacol. 20C: 14-23 |
| • Zhu, S.*, Riou, M.*, Yao, A., Carvalho, S., Rodriguez, P., Bensaude, O., Paoletti, P.#, Ye, S.#. (2014) Genetically encoding a light-switch in an ionotropic glutamate receptor reveals subunit-specific interfaces. Proc Natl Acad Sci U S A. 111(16): 6081-6 |
| • Stroebel, D., Carvalho, S., Grand, T., Zhu, S., Paoletti, P.# (2014) Controlling NMDA Receptor Subunit Composition Using Ectopic Retention Signals. J Neurosci. 34(50): 16630-6 |
| • Zhu, S.*, Stroebel, D., C.Andrea, Y., Taly, A., Paoletti, P.# (2013) Allosteric signaling and dynamics of the clamshell-like NMDA receptor GluN1 N-terminal domain. Nat. Struct. Mol. Biol. 20: 477-485 |
| • Mony, L.*, Zhu, S.*, Carvalho, S., Paoletti, P.# (2011) Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines. EMBO J. 30(15): 3134-3146 |
